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Researchers from Guy’s and St Thomas’ and King’s College London have discovered a surprising potential for a common mouth bacterium, Fusobacterium, to combat certain cancers. This bacterium, typically found in the mouth, appears to have a remarkable ability to "melt" cancer cells, particularly in head and neck cancers. In laboratory studies, Fusobacterium was found to kill up to 99% of these cancer cells, significantly reducing the number of viable cancer cells within days.
The scientists were initially taken aback by these findings, as Fusobacterium has previously been associated with the progression of other cancers, such as colorectal cancer. The discovery could open new avenues for cancer treatment, especially since patients with head and neck cancers who had this bacterium within their tumors experienced much better outcomes (Ground News) (TROMnews) (Democratic Underground). Further research is underway to understand the mechanisms behind this effect, with hopes of developing new therapeutic strategies.
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Toothaches can be incredibly disruptive and painful, often indicating an underlying dental issue that needs attention. Here’s a step-by-step guide on what to do if you or someone you know experiences a toothache.
1. Assess the Pain
Determine the severity and location of the pain. Is it sharp or dull? Constant or intermittent? Knowing these details can help your dentist diagnose the problem more accurately.
2. Rinse Your Mouth
Use warm water to rinse your mouth thoroughly. This can help dislodge any food particles stuck between your teeth and provide some relief.
3. Floss Carefully
Gently floss around the affected tooth to remove any debris that could be causing irritation. Be careful not to push too hard, as this could exacerbate the pain.
4. Apply a Cold Compress
If there is swelling, apply a cold compress to the outside of your cheek near the affected area. This can help reduce inflammation and numb the pain temporarily.
5. Take Over-the-Counter Pain Relievers
Non-prescription pain relievers such as ibuprofen or acetaminophen can help manage the pain until you can see your dentist. Always follow the dosage instructions on the label.
6. Avoid Certain Foods
Stay away from very hot, cold, sugary, or acidic foods and drinks, as they can aggravate a toothache. Stick to soft foods that are easy to chew.
7. Use Clove Oil
Clove oil has natural numbing properties. Soak a cotton ball in a few drops of clove oil and apply it to the affected tooth. Be careful not to use too much, as it can cause irritation.
8. See Your Dentist
A toothache is often a sign of a more serious problem such as a cavity, infection, or gum disease. It’s crucial to schedule an appointment with your dentist as soon as possible to get a proper diagnosis and treatment.
9. Practice Good Oral Hygiene
Maintaining a good oral hygiene routine can help prevent future toothaches. Brush your teeth twice a day, floss daily, and use mouthwash to keep your mouth clean and healthy.
10. Follow-Up Care
After your dental appointment, follow your dentist’s advice for any follow-up care or treatment. This might include taking prescribed medications, avoiding certain foods, or scheduling additional visits.
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Researchers from Pusan National University have discovered how diabetes weakens gum defense, linking periodontitis and diabetes mellitus through altered immune cell function and the RESISTIN pathway. Their study, using single-cell RNA analysis, revealed immune changes at the cellular level, suggesting periodontitis could be a precursor to diabetes. This research could lead to targeted interventions for patients with periodontitis to reduce their risk of developing diabetes. For more details, you can read the full article on Medical Xpress.
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A dental crown is essentially a cap that is custom-made to fit over a damaged or weakened tooth. It's commonly used to restore the shape, appearance, and functionality of the tooth. Here are some specifics:
How It Works:
- Evaluation: First, the dentist evaluates the condition of the tooth in question to determine if a crown is the appropriate solution.
- Preparation: The tooth is filed down to make room for the crown. In some cases, a filling material may be used to build up the tooth.
- Impression: An impression of the prepared tooth and surrounding teeth is taken. This is usually sent to a dental lab where the crown is made.
- Temporary Crown: A temporary crown is often placed to protect the prepared tooth while the permanent crown is being made.
- Fitting: Once the permanent crown is ready, the dentist will remove the temporary crown and cement the permanent one in place, making adjustments as necessary.
Benefits:
- Restores Functionality: Crowns restore a tooth's shape and function, allowing for regular eating and speaking activities.
- Cosmetic Improvement: Crowns can greatly improve the appearance of discolored, misshapen, or otherwise aesthetically unpleasant teeth.
- Protection: A crown adds a layer of protection to a weakened or damaged tooth, preventing further decay or deterioration.
- Longevity: Dental crowns are usually made of durable materials like porcelain, ceramic, or metal, which can last many years if properly cared for.
- Comfort: Because they are custom-made, crowns are designed to fit comfortably in your mouth.
- Support for Adjacent Teeth: A crowned tooth provides support to adjacent teeth, which can be beneficial for your overall dental health.
- Versatility: Crowns can be used in conjunction with other dental procedures like bridges and implants, making them versatile solutions for various dental problems.
However, it's essential to consult a qualified dental professional for an accurate diagnosis and treatment plan tailored to your specific needs.